Welcome to MedTech Frontiers
A Monthly Event Hosted by Triple Ring Technologies
MedTech Frontiers is a continuing series of free events for medical device and life science investors, entrepreneurs, and technologists. Please join us for evenings of food, conversation, and presentations by Silicon Valley luminaries held on the first Thursday of each month.
Date: Thursday, February 5, 2015
Time: 6:00 pm - 9:00 pm
Triple Ring Technologies,
39655 Eureka Dr. Newark CA
Speaker: Amy E. Herr, PhD
Cost: The seminar is free of charge, but advance registration is required
On-Site registration: A limited number of on-site registrations may be available
About the Seminar:Biology is becoming quantitative. Technology advances have driven a genomics revolution with sweeping impact on our understanding of life processes. Nevertheless, the arguably more important "proteomics revolution" remains unrealized. While microfluidic technology has advanced separations science, progress lags in the multi-stage separations that are a hallmark of proteomics. This talk will summarize new microengineering design for critical multi-stage protein assays. I will detail our tunable photopatterned materials for switchable function, microfluidic architectures for seamless integration of discrete stages, and multiplexed readouts for quantitation. As specific case studies, I will discuss a spectrum of translational measurements my group is making possible: from near-patient diagnostics for HIV confirmation to biomarker validation of cancer signaling isoforms to single-cell Western blotting of pathway activation during neural stem cell differentiation. Performance and operational gains will be discussed, including quantitation capability, total assay automation, and minimization of dispersion to maximize information content. Ultimately, our work infuses protein measurement advances into the biological and biomedical sciences.
About the Presenter:Professor Amy E. Herr received her BS degree from Caltech and her MS and PhD degrees from Stanford in Mechanical Engineering. Prior to joining the faculty at UC Berkeley, Prof. Herr was a Biosystems Research staff member at Sandia National Laboratories (Livermore). At UC Berkeley since 2007, Prof. Herr's research focuses on instrumentation innovation to advance quantitation in life sciences and clinical problems - impact spans from tools for fundamental research (cell signaling) to near-patient disease diagnostics. Her major awards include: the 2012 Young Innovator Award from Analytical Chemistry and the Chemical & Biological Microsystems Society, the 2012 Ellen Weaver Award from the Association for Women in Science (AWIS), a 2012 Bakar Fellowship at UC Berkeley, a 2011 NSF CAREER Award, the 2011 Eli Lilly & Co. New Investigator Award in analytical chemistry, a 2010 NIH New Innovator Award, a 2010 Alfred P. Sloan Research Fellowship (chemistry), a 2009 DARPA Young Faculty Award, the 2009 Hellman Family Faculty Fund Award from UC Berkeley, and the 2008 Regents' Junior Faculty Fellowship from UC. She Chaired (2009) & Vice-chaired (2007) the Gordon Research Conference (GRC) on the Physics & Chemistry of Microfluidics. Professor Herr is an elected Fellow of the American Institute of Medical and Biological Engineering (AIMBE), a standing member of the NIH Nanotechnology Study Section, a Board member of the Chemical & Biological Microsystems Society (CMBS, oversees the microTAS conferences), and is on the Advisory Boards for the UCSF Rosenman Institute and the journal Analytical Chemistry.
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