Key Innovation
By utilizing a computational breakthrough, we turned a pocket-sized device into a tool capable of synthesizing clinical-grade cardiac diagnostics.
Cable-Free Synthesized ECG
Client
HeartBeam
Practice Areas
Core Disciplines
Overview
HeartBeam collaborated with Triple Ring to develop an innovative telehealth solution designed to transform the detection and monitoring of cardiac conditions. The goal was to create a compact, portable cardiac monitoring device capable of collecting ECG signals in three dimensions and synthesizing them into a clinically meaningful 12-lead ECG.
The resulting platform supports remote cardiac monitoring by enabling physicians to access real-time data outside traditional clinical settings, expanding access to cardiac diagnostics and improving patient care workflows.
Challenge
HeartBeam sought to develop a personal, cable-free, and easy-to-use cardiac monitoring solution for both in-clinic and at-home use. The objective was to create a credit card-sized ECG recording device that leverages vectorcardiography (VECG) and integrates with cloud-based software to deliver critical patient data to physicians in real time.
Achieving this required coordinating multidisciplinary device development while meeting regulatory requirements and supporting rapid product development timelines.
Solution
HeartBeam partnered with Triple Ring to execute a comprehensive, five-phase expedited device development program spanning early R&D, industrial design, product development, manufacturing readiness, and regulatory preparation.
Triple Ring applied expertise in wearable medical device design and system integration to develop the cable-free ECG device and supporting ecosystem. The program included device builds for design verification and validation, packaging development, and manufacturing technology transfer to support scalable production.
Key development activities included:
- Designing compact wearable hardware capable of capturing three-dimensional ECG signals
- Integrating smartphone-based communication to transmit data securely
- Developing cloud-connected workflows that enabled remote physician access
- Supporting regulatory preparation for FDA 510(k) submission and validation
Cable-Free Synthesized ECG
Overview
HeartBeam collaborated with Triple Ring to develop an innovative telehealth solution designed to transform the detection and monitoring of cardiac conditions. The goal was to create a compact, portable cardiac monitoring device capable of collecting ECG signals in three dimensions and synthesizing them into a clinically meaningful 12-lead ECG.
The resulting platform supports remote cardiac monitoring by enabling physicians to access real-time data outside traditional clinical settings, expanding access to cardiac diagnostics and improving patient care workflows.
Challenge
HeartBeam sought to develop a personal, cable-free, and easy-to-use cardiac monitoring solution for both in-clinic and at-home use. The objective was to create a credit card-sized ECG recording device that leverages vectorcardiography (VECG) and integrates with cloud-based software to deliver critical patient data to physicians in real time.
Achieving this required coordinating multidisciplinary device development while meeting regulatory requirements and supporting rapid product development timelines.
Solution
HeartBeam partnered with Triple Ring to execute a comprehensive, five-phase expedited device development program spanning early R&D, industrial design, product development, manufacturing readiness, and regulatory preparation.
Triple Ring applied expertise in wearable medical device design and system integration to develop the cable-free ECG device and supporting ecosystem. The program included device builds for design verification and validation, packaging development, and manufacturing technology transfer to support scalable production.
Key development activities included:
- Designing compact wearable hardware capable of capturing three-dimensional ECG signals
- Integrating smartphone-based communication to transmit data securely
- Developing cloud-connected workflows that enabled remote physician access
- Supporting regulatory preparation for FDA 510(k) submission and validation
Client
HeartBeam
Practice Areas
Core Disciplines
Outcome
The HeartBeam–Triple Ring collaboration produced a personal, cable-free synthesized 12-lead ECG solution that enables patients to record cardiac data at home. The device integrates with a smartphone application that communicates with the HeartBeam Cloud, where synthesized ECG data is compared with baseline records and made available to physicians remotely.
This multidisciplinary and fast-paced program resulted in a successful 510(k) submission to the U.S. Food and Drug Administration (FDA) and regulatory clearance in 2024 for the hardware that leverages vectorcardiography and collects 3D ECG data. The synthesized 12-lead ECG algorithm remains pending FDA clearance.
The completed system enables physicians to remotely monitor cardiac conditions and guide patient care outside traditional healthcare facilities, supporting new models of telehealth-enabled cardiac diagnostics.
Triple Ring Talent
The Story Behind the Innovation
At Triple Ring, we draw on a deep bench of expertise across diverse disciplines matched to each innovation challenge. For this project, our team applied expertise in wearable medical device design, system integration, and regulatory strategy to deliver a cable-free, credit card-sized ECG device — from early R&D through successful FDA 510(k) clearance in 2024.
Walt and Kevin collaborated with many talented colleagues across Triple Ring and HeartBeam on this project.
Walt Cecka
Medical Device Design & Translational Medicine
Walt Cecka brings decades of experience translating novel medical technologies into first-to-market products. He works closely with innovators to shape early concepts into structured development programs that advance patient care across a wide range of clinical applications.
Kevin Dunk
Mechanical & Aerospace Engineering
Kevin Dunk brings expertise in mechanical engineering and multidisciplinary product development across the full device lifecycle. His work supports teams from early prototypes through verification and manufacturing, helping ensure systems are reliable, scalable, and ready for real-world use.
Key Innovation
By inverting the conventional radiotherapy model, and keeping the beam fixed while rotating the patient, we enabled a compact, upright treatment platform without sacrificing clinical precision.
Upright Radiation Therapy
Client
Leo Cancer Care
Practice Areas
Core Disciplines
Overview
Leo Cancer Care worked with Triple Ring to design a computed tomography (CT) imaging system supporting a novel radiation therapy concept that enables treatment in a natural, upright seated position. The system integrates imaging and patient positioning into a single device, allowing patients to be scanned in both upright and lying positions.
This platform introduces a new approach to radiotherapy delivery by improving patient comfort, positioning accuracy, and overall treatment workflow.
Challenge
Leo Cancer Care sought to develop a radiation therapy system capable of imaging and positioning patients in an upright configuration while maintaining the precision and safety required for clinical use. The concept required rethinking traditional radiotherapy architectures, including replacing large rotating gantries with a fixed-beam, slow patient rotation strategy.
Achieving this capability required overcoming mechanical, imaging, and system integration challenges while ensuring reliable clinical performance across multiple operating modes.
Upright Radiation Therapy
Overview
Leo Cancer Care worked with Triple Ring to design a computed tomography (CT) imaging system supporting a novel radiation therapy concept that enables treatment in a natural, upright seated position. The system integrates imaging and patient positioning into a single device, allowing patients to be scanned in both upright and lying positions.
This platform introduces a new approach to radiotherapy delivery by improving patient comfort, positioning accuracy, and overall treatment workflow.
Challenge
Leo Cancer Care sought to develop a radiation therapy system capable of imaging and positioning patients in an upright configuration while maintaining the precision and safety required for clinical use. The concept required rethinking traditional radiotherapy architectures, including replacing large rotating gantries with a fixed-beam, slow patient rotation strategy.
Achieving this capability required overcoming mechanical, imaging, and system integration challenges while ensuring reliable clinical performance across multiple operating modes.
Client
Leo Cancer Care
Practice Areas
Core Disciplines
Solution
Triple Ring applied expertise in radiotherapy physics, imaging systems, and mechanical engineering to design a gantry architecture supporting upright and traditional patient positioning. Close collaboration enabled integration of multiple subsystems into a unified clinical platform.
Key engineering efforts included:
- Designing multi-axis motion systems that supported upright and reclined patient positioning
- Applying radiotherapy physics expertise to guide system architecture
- Using advanced modeling and simulation tools to validate mechanical alignment and imaging accuracy
- Integrating imaging and positioning subsystems into a unified platform
Outcome
The collaboration resulted in an innovative gantry design supporting upright radiation therapy workflows and enabling alternative approaches to traditional radiotherapy systems.
The platform advanced the development of upright radiation therapy as a viable treatment approach, supporting improved patient comfort and positioning accuracy.
Triple Ring Talent
The Story Behind the Innovation
At Triple Ring, we draw on a deep bench of expertise across diverse disciplines matched to each innovation challenge. For this project, our team applied radiotherapy physics, large-scale mechanical design, and systems integration expertise to develop a novel gantry architecture enabling patients to receive radiation therapy in a natural, upright seated position.
Tachi and Tobias collaborated with many talented colleagues across Triple Ring and Leo Cancer Care on this project.
Tachi Callas
Mechanical Engineering
Tachi Callas leads mechanical engineering teams developing complex medical technologies across the full product lifecycle. His work helps transform innovative device concepts into manufacturable systems that support advanced surgical and therapeutic applications.
Tobias Funk, PhD
Experimental Physics & Instrumentation
Dr. Tobias Funk develops advanced instrumentation that applies ionizing radiation to scientific and medical challenges. His work spans imaging, simulation, and system design, helping translate complex physical principles into practical technologies used in real-world environments.
Key Innovation
By integrating motion correction into the CT imaging system, we eliminated the need for general anesthesia — reducing equine patient risk while preserving diagnostic image quality.
Next-Generation Equine Imaging
Client
Prisma Imaging
Practice Areas
Core Disciplines
Overview
Prisma Imaging collaborated with Triple Ring to design, model, build, and test a functional prototype equine CT scanner for use in veterinary clinic settings. The system was developed to generate high-quality images of live horses while supporting safer workflows compared to traditional imaging methods.
The resulting platform combined robotic motion systems, imaging technology, and motion correction capabilities to enable imaging of large animals without requiring general anesthesia.
Challenge
Prisma Imaging sought to develop a CT imaging system capable of safely scanning live equine patients. Traditional imaging workflows often require anesthesia, introducing additional risk and logistical complexity.
The project required integrating robotic gantry motion, X-ray imaging, radiation safety, motion capture, and CT reconstruction into a unified system architecture capable of handling natural patient movement.
Next-Generation Equine Imaging
Overview
Prisma Imaging collaborated with Triple Ring to design, model, build, and test a functional prototype equine CT scanner for use in veterinary clinic settings. The system was developed to generate high-quality images of live horses while supporting safer workflows compared to traditional imaging methods.
The resulting platform combined robotic motion systems, imaging technology, and motion correction capabilities to enable imaging of large animals without requiring general anesthesia.
Challenge
Prisma Imaging sought to develop a CT imaging system capable of safely scanning live equine patients. Traditional imaging workflows often require anesthesia, introducing additional risk and logistical complexity.
The project required integrating robotic gantry motion, X-ray imaging, radiation safety, motion capture, and CT reconstruction into a unified system architecture capable of handling natural patient movement.
Client
Prisma Imaging
Practice Areas
Core Disciplines
Solution
Triple Ring applied cross-disciplinary engineering expertise and systems engineering methodologies to design and integrate a complex imaging platform capable of supporting live-animal imaging.
Key elements of the solution included:
- Designing a robotic gantry capable of supporting controlled positioning of large animal patients
- Developing motion tracking and correction technologies to compensate for natural movement
- Integrating X-ray imaging subsystems capable of producing high-resolution diagnostic images
- Validating system performance through live-animal imaging under controlled conditions
Outcome
Triple Ring delivered a gantry-mounted CT imaging system capable of imaging horses under conscious sedation rather than general anesthesia.
The integrated motion tracking and correction system maintained imaging quality comparable to standard CT systems, enabling full-body imaging across equine anatomy without anesthesia.
Triple Ring Talent
The Story Behind the Innovation
At Triple Ring, we draw on a deep bench of expertise across diverse disciplines matched to each innovation challenge. For this project, our team combined robotic systems design, CT imaging, motion capture and correction, and systems integration expertise to deliver a functional equine CT scanner capable of imaging conscious, sedated horses without general anesthesia.
Meet our team Tobias Funk, PhD
Experimental Physics & Instrumentation
Dr. Tobias Funk develops advanced instrumentation that applies ionizing radiation to scientific and medical challenges. His work spans imaging, simulation, and system design, helping translate complex physical principles into practical technologies used in real-world environments.
Quinn La
Electrical Technician
Quinn La oversees the build and validation of complex electrical and electro-mechanical systems across development programs. His work supports board bring-up, testing, and manufacturing processes, ensuring systems are assembled, debugged, and prepared for reliable operation.
Key Innovation
By coupling high-speed laser-based optical imaging with machine learning workflows, we compressed oncology tissue analysis timelines from days to minutes — directly inside the OR.
Intra-Operative Tissue Pathology
Client
BlackLight Surgical
Core Disciplines
Overview
BlackLight Surgical engaged Triple Ring to develop a high-speed biochemical imaging platform designed for intra-operative tissue analysis. The system leveraged picosecond pulsing laser technology and machine learning workflows to enable rapid tissue identification during surgical procedures.
The resulting platform supports real-time clinical decision making by allowing clinicians to distinguish between normal and diseased tissue directly in the operating suite.
Challenge
The system required integration of advanced optical imaging technology capable of performing rapid biochemical analysis during surgery. Reliable performance was required across demanding clinical environments and complex workflows.
Delivering this capability required precise integration of optical, mechanical, software, and machine learning systems into a clinically deployable architecture.
Intra-Operative Tissue Pathology
Overview
BlackLight Surgical engaged Triple Ring to develop a high-speed biochemical imaging platform designed for intra-operative tissue analysis. The system leveraged picosecond pulsing laser technology and machine learning workflows to enable rapid tissue identification during surgical procedures.
The resulting platform supports real-time clinical decision making by allowing clinicians to distinguish between normal and diseased tissue directly in the operating suite.
Challenge
The system required integration of advanced optical imaging technology capable of performing rapid biochemical analysis during surgery. Reliable performance was required across demanding clinical environments and complex workflows.
Delivering this capability required precise integration of optical, mechanical, software, and machine learning systems into a clinically deployable architecture.
Client
BlackLight Surgical
Core Disciplines
Solution
Triple Ring assembled multidisciplinary engineering and scientific teams to design and integrate the imaging platform using structured development and validation methodologies.
Technical execution focused on:
- Integrating laser-based optical imaging technologies capable of rapid tissue analysis
- Developing machine learning workflows that supported real-time tissue classification
- Using simulation and modeling tools to guide system design and performance optimization
- Establishing ISO 13485-compliant design and documentation processes
Outcome
Triple Ring delivered a fully integrated intra-operative biochemical imaging platform supporting clinical studies and real-time tissue visualization.
The system was developed to ISO 13485 standards and documented within a Quality Management System transferred to BlackLight Surgical, enabling deployment of advanced intra-operative imaging workflows.
Triple Ring Talent
The Story Behind the Innovation
At Triple Ring, we draw on a deep bench of expertise across diverse disciplines matched to each innovation challenge. For this project, our team combined high-speed laser optical imaging, machine learning, mechanical engineering, and quality systems expertise to develop a fully integrated intra-operative tissue analysis platform capable of distinguishing healthy from diseased tissue in real time.
Todd, Cameran, and Shehadeh collaborated with many talented colleagues across Triple Ring and BlackLight Surgical on this project.
Todd Harris, PhD
Physics & Optical Science
Dr. Todd Harris applies expertise in optics and imaging physics to the development of advanced sensing and illumination technologies. His work combines optical modeling with system design, helping teams translate complex physical principles into dependable, high-performance solutions.
Cameran Casale
Bioengineering
Cameran Casale contributes to the development of imaging, microfluidic, and diagnostic technologies across multidisciplinary programs. Her work supports system integration and testing efforts, helping teams refine complex devices for reliable performance in research and clinical environments.
Shehadeh Dajani
Aerospace & Mechanical Engineering
Shehadeh Dajani supports the development of safety-critical embedded systems used in regulated medical technologies. His work spans software and system integration across feasibility, clinical, and production stages, helping ensure reliable performance throughout the development lifecycle.
Key Innovation
By coupling wearable optics with injectable dyes, we enabled continuous, non-invasive kidney monitoring without repeated blood draws or lab visits.
Transdermal GFR Measurement
Client
MediBeacon
Practice Areas
Core Disciplines
Overview
MediBeacon partnered with Triple Ring to develop a photonics-based transdermal detection system designed to measure kidney function using fluorescent tracer technology. The system enables non-invasive monitoring of intravenously injected tracers to generate clinically actionable measurements of glomerular filtration rate (GFR).
The resulting wearable detection platform integrates optical sensing and physiological measurement technologies to support real-time kidney function assessment in clinical environments.
Challenge
MediBeacon required development of a wearable optical detection system capable of monitoring fluorescent tracer signals through human tissue. The system needed to achieve high sensitivity and accuracy while remaining comfortable and practical for clinical use.
In addition to performance requirements, the device needed to meet strict constraints related to cost, usability, and manufacturability. The development effort required careful balancing of optical performance, ergonomic design, and regulatory compliance within a wearable form factor.
Transdermal GFR Measurement
Overview
MediBeacon partnered with Triple Ring to develop a photonics-based transdermal detection system designed to measure kidney function using fluorescent tracer technology. The system enables non-invasive monitoring of intravenously injected tracers to generate clinically actionable measurements of glomerular filtration rate (GFR).
The resulting wearable detection platform integrates optical sensing and physiological measurement technologies to support real-time kidney function assessment in clinical environments.
Challenge
MediBeacon required development of a wearable optical detection system capable of monitoring fluorescent tracer signals through human tissue. The system needed to achieve high sensitivity and accuracy while remaining comfortable and practical for clinical use.
In addition to performance requirements, the device needed to meet strict constraints related to cost, usability, and manufacturability. The development effort required careful balancing of optical performance, ergonomic design, and regulatory compliance within a wearable form factor.
Client
MediBeacon
Practice Areas
Core Disciplines
Solution
Triple Ring collaborated closely with MediBeacon to design and deliver a non-invasive wearable detection system capable of supporting accurate GFR measurement. The development effort leveraged expertise in light-based tissue analysis and system-level modeling to optimize detection performance while supporting user comfort and clinical usability.
The team addressed these challenges by:
- Applying advanced photonics expertise to optimize signal detection through tissue
- Using modeling and simulation tools to refine optical system performance
- Designing wearable hardware that supported patient comfort during extended use
- Aligning development processes with clinical validation and regulatory expectations
Outcome
Fully integrated wearable GFR detection systems were developed under ISO 13485 design controls and delivered to support critical clinical trials. The resulting devices enabled accurate, non-invasive measurement of kidney function through optical detection of fluorescent tracers.
The platform supported the advancement of MediBeacon’s GFR monitoring technology toward clinical validation, enabling real-time physiological measurement while maintaining patient comfort and usability.
Triple Ring Talent
The Story Behind the Innovation
At Triple Ring, we draw on a deep bench of expertise across diverse disciplines matched to each innovation challenge. For this project, our team combined photonics, transdermal optical sensing, wearable device design, and advanced simulation expertise to develop a clinical-grade wearable system capable of measuring kidney function non-invasively through fluorescent tracer detection.
Gus and Ed collaborated with many talented colleagues across Triple Ring and MediBeacon on this project.
Gus Lowell
Systems Architecture & Electrical Engineering
Augustus “Gus” Lowell defines the architecture of complex software and hardware systems across multidisciplinary programs. His work establishes the frameworks that connect data processing, control, and safety-critical functions, helping ensure technologies operate reliably as integrated systems.
Ed Solomon
Electrical Engineering & Advanced Technologies
Ed Solomon connects advanced engineering with business strategy to help bring innovative technologies into practical use. His work supports system architecture, partnership development, and technology adoption, helping organizations move complex ideas toward successful deployment.
Key Innovation
By packaging continuous biometric and wireless monitoring into an animal-ready wearable, we unlocked a new standard of veterinary care.
Veterinary Vital Sign Monitor
Client
One Health Group
Practice Areas
Core Disciplines
Overview
One Health Group partnered with Triple Ring to develop a non-invasive wearable physiological monitoring system designed to capture biometric data from animals in real time. The system was developed to support continuous health monitoring in veterinary settings while improving patient comfort and enabling early detection of health issues.
The resulting wearable platform integrates physiological sensing and wireless communication technologies to enable long-term monitoring and provide actionable health insights for veterinary care providers.
Challenge
One Health Group required development of a wearable monitoring device capable of accurately measuring physiological signals in animals while remaining comfortable and suitable for continuous use. The system needed to support long-term data collection and deliver real-time alerts without interfering with normal animal movement.
As a lean startup organization, One Health Group relied on a fully outsourced R&D model. The project required multidisciplinary engineering expertise to design, prototype, and validate a complex sensing platform while rapidly demonstrating feasibility and reducing development risk.
Veterinary Vital Sign Monitor
Overview
One Health Group partnered with Triple Ring to develop a non-invasive wearable physiological monitoring system designed to capture biometric data from animals in real time. The system was developed to support continuous health monitoring in veterinary settings while improving patient comfort and enabling early detection of health issues.
The resulting wearable platform integrates physiological sensing and wireless communication technologies to enable long-term monitoring and provide actionable health insights for veterinary care providers.
Challenge
One Health Group required development of a wearable monitoring device capable of accurately measuring physiological signals in animals while remaining comfortable and suitable for continuous use. The system needed to support long-term data collection and deliver real-time alerts without interfering with normal animal movement.
As a lean startup organization, One Health Group relied on a fully outsourced R&D model. The project required multidisciplinary engineering expertise to design, prototype, and validate a complex sensing platform while rapidly demonstrating feasibility and reducing development risk.
Client
One Health Group
Practice Areas
Core Disciplines
Solution
Triple Ring led the development of a wearable physiological monitoring platform using a structured feasibility and product development approach. Industrial design, sensing technologies, and system integration were coordinated to ensure reliable performance and comfort across extended wear conditions.
Key contributions included:
- Designing wearable hardware capable of supporting continuous physiological monitoring
- Conducting rapid feasibility testing to validate sensing and alert functionality
- Refining industrial design to improve comfort, usability, and durability
Outcome
Triple Ring delivered robust functional prototypes capable of generating high-quality physiological data suitable for ongoing product development and validation. The system demonstrated the feasibility of continuous biometric monitoring in veterinary applications.
The successful development effort supported One Health Group’s technology roadmap and strengthened its value proposition, enabling expanded partnerships with strategic investors in the veterinary health industry.
Triple Ring Talent
The Story Behind the Innovation
At Triple Ring, we draw on a deep bench of expertise across diverse disciplines matched to each innovation challenge. For this project, our team combined physiological sensing, wireless systems, industrial design, and startup-focused R&D expertise to develop a wearable continuous monitoring platform capable of capturing real-time biometric data from animals in veterinary settings.
Brian and Steve collaborated with many talented colleagues across Triple Ring and One Health Group on this project.
Brian Wilfley, PhD
Experimental Physics & Instrumentation
Dr. Brian Wilfley leads the development of complex measurement and instrumentation systems grounded in experimental physics. His work combines theoretical insight with hands-on experimentation to advance technologies used in imaging, inspection, and scientific analysis.
Steve Kuhn
Embedded Systems & Software Engineering
Steve Kuhn develops embedded software and real-time control systems that support complex hardware-driven technologies. His work focuses on software architecture, motion control, and system simulation, enabling reliable operation across integrated device platforms.
Key Innovation
By taking a simulation-driven approach to x-ray source and robotic integration, we accelerated a novel intraoperative radiation therapy system from concept to FDA clearance.
Robotic Radiation Therapy
Client
Empyrean Medical Systems
Practice Areas
Core Disciplines
Overview
Empyrean Medical Systems worked with Triple Ring to design and develop a compact, robotically guided intra-operative radiation therapy device. The system was engineered to deliver targeted radiation therapy within surgical environments while maintaining a strong focus on usability and patient-centered design.
The resulting platform combined robotic guidance, precision radiation delivery, and mobile system architecture to support flexible clinical workflows and improve intra-operative treatment capabilities.
Challenge
Empyrean required development of a compact, mobile radiation therapy system capable of delivering low-energy radiation with precise beam directionality during surgical procedures. The system needed to maintain high performance standards while remaining easy to operate within the constraints of clinical environments.
In addition to performance requirements, the platform required integration of multiple complex subsystems, including custom x-ray sources, beam steering electronics, and robotic positioning components. The development effort also required preparation of a complete design package supporting regulatory submission.
Robotic Radiation Therapy
Overview
Empyrean Medical Systems worked with Triple Ring to design and develop a compact, robotically guided intra-operative radiation therapy device. The system was engineered to deliver targeted radiation therapy within surgical environments while maintaining a strong focus on usability and patient-centered design.
The resulting platform combined robotic guidance, precision radiation delivery, and mobile system architecture to support flexible clinical workflows and improve intra-operative treatment capabilities.
Challenge
Empyrean required development of a compact, mobile radiation therapy system capable of delivering low-energy radiation with precise beam directionality during surgical procedures. The system needed to maintain high performance standards while remaining easy to operate within the constraints of clinical environments.
In addition to performance requirements, the platform required integration of multiple complex subsystems, including custom x-ray sources, beam steering electronics, and robotic positioning components. The development effort also required preparation of a complete design package supporting regulatory submission.
Client
Empyrean Medical Systems
Practice Areas
Core Disciplines
Solution
Triple Ring collaborated with Empyrean throughout the full product development lifecycle, from concept generation through system integration and clinical validation. The engineering effort focused on delivering precise radiation delivery capabilities while maintaining usability and manufacturability.
Development priorities included:
- Designing custom x-ray source technologies supporting 3D beam directionality
- Applying Monte Carlo simulations to validate radiation delivery performance
- Integrating robotic motion systems supporting accurate positioning
- Preparing documentation supporting FDA regulatory submission
Outcome
Triple Ring delivered a fully integrated radiation therapy system that was verified, clinically validated, and submitted to the U.S. Food and Drug Administration (FDA) for 510(k) clearance. The resulting platform supported regulatory approval and demonstrated reliable clinical performance.
Following regulatory submission, the system design was successfully transferred to manufacturing and launched into the market. The completed platform enabled advancement of intra-operative radiation therapy capabilities and supported commercialization of the robotic radiation delivery system.
Triple Ring Talent
The Story Behind the Innovation
At Triple Ring, we draw on a deep bench of expertise across diverse disciplines matched to each innovation challenge. For this project, our team combined radiation physics, custom x-ray source development, robotic systems integration, and regulatory engineering expertise to deliver a fully verified, FDA-submitted intra-operative radiation therapy platform from concept through market launch.
Chris and Barry collaborated with many talented colleagues across Triple Ring and Empyrean Medical Systems on this project.
Chris Mitchell, PhD
Bio and Electrical Engineering & Program Management
Dr. Chris Mitchell brings deep experience leading multidisciplinary teams developing complex imaging and medical device systems. His work focuses on guiding technical programs from concept through implementation, helping translate advanced technologies into reliable, real-world solutions.
Barry Wood
Biomedical & Mechanical Engineering
Barry Wood develops mechanical and biomedical systems with a focus on design and performance analysis. His work supports the creation of robust solutions for complex applications, contributing to dependable system function from concept through implementation.
Key Innovation
By introducing quantitation to lateral flow immunoassays through integrated optical and embedded systems, we brought high-quality multiplexed diagnostics within reach of the home and low-resource settings.
At-Home Quantitative Diagnostics
Client
BARDA
Practice Areas
Core Disciplines
Overview
The Biomedical Advanced Research and Development Authority (BARDA) selected Triple Ring to design, build, and test a low-cost quantitative biomarker detection platform intended for at-home and low-resource healthcare settings. The system was developed to support multiplexed biomarker analysis using compact, user-friendly instrumentation.
The resulting platform integrates biological sensing, embedded electronics, and optical detection technologies into a portable diagnostic system designed to support lab-at-home, point-of-care, and direct-to-consumer workflows.
Challenge
BARDA identified the need for a low-cost diagnostic platform capable of delivering quantitative biomarker measurements outside traditional laboratory environments. The system needed to support multiplexed testing while remaining accessible for use in resource-limited settings and CLIA-waived environments.
Achieving this capability required integration of complex biological, optical, and electronic subsystems into a compact and manufacturable design. The platform also needed to extend the measurable range of lateral flow immunoassays while maintaining usability and cost targets suitable for broad deployment.
At-Home Quantitative Diagnostics
Overview
The Biomedical Advanced Research and Development Authority (BARDA) selected Triple Ring to design, build, and test a low-cost quantitative biomarker detection platform intended for at-home and low-resource healthcare settings. The system was developed to support multiplexed biomarker analysis using compact, user-friendly instrumentation.
The resulting platform integrates biological sensing, embedded electronics, and optical detection technologies into a portable diagnostic system designed to support lab-at-home, point-of-care, and direct-to-consumer workflows.
Challenge
BARDA identified the need for a low-cost diagnostic platform capable of delivering quantitative biomarker measurements outside traditional laboratory environments. The system needed to support multiplexed testing while remaining accessible for use in resource-limited settings and CLIA-waived environments.
Achieving this capability required integration of complex biological, optical, and electronic subsystems into a compact and manufacturable design. The platform also needed to extend the measurable range of lateral flow immunoassays while maintaining usability and cost targets suitable for broad deployment.
Client
BARDA
Practice Areas
Core Disciplines
Solution
Triple Ring applied multidisciplinary expertise across biological sciences, engineering, and embedded systems to develop a scalable diagnostic platform capable of delivering quantitative results from multiplexed lateral flow assays.
Development efforts focused on:
- Designing multiplexed lateral flow assay (LFA) detection systems capable of quantifying biomarker concentrations
- Integrating biological, electrical, mechanical, optical, and embedded software subsystems into a unified platform
- Developing workflows suitable for CLIA-waived, point-of-care, and at-home diagnostic environments
- Extending the quantitative measurement range beyond that of conventional lateral flow assay readers
- Conducting system-level integration and verification to support development of a handheld diagnostic platform
Outcome
Triple Ring delivered a functional multiplexed diagnostic platform capable of quantifying biomarker concentrations across multiple test channels. The system demonstrated improved quantitative measurement range compared to conventional lateral flow assay readers.
The platform supported deployment across diverse clinical environments, including at-home and point-of-care settings. Ongoing development efforts include system integration and testing of a handheld version designed to further expand accessibility and usability in remote and low-resource healthcare environments.
Triple Ring Talent
The Story Behind the Innovation
At Triple Ring, we draw on a deep bench of expertise across diverse disciplines matched to each innovation challenge. For this project, our team combined biological sciences, optical detection, embedded electronics, and diagnostic platform engineering to develop a low-cost multiplexed biomarker detection system capable of delivering quantitative lab-grade results in at-home and resource-limited healthcare settings.
Rachel and Chris collaborated with many talented colleagues across Triple Ring and BARDA on this project.
Rachel Gerver, PhD
Bioengineering & Applied Science and Systems
Dr. Rachel Gerver advances microfluidic and point-of-care technologies from early development into real-world application. Her work spans technical leadership and systems development, helping teams bring complex innovations to market where they can deliver meaningful impact.
Chris Todd
Mechanical Engineering
Chris Todd focuses on biomedical diagnostics and precision instrumentation, integrating fluidics, optics, and mechanical systems. His work supports the development of regulated medical technologies from early concepts through manufacturing, helping teams deliver reliable diagnostic solutions at scale.
Key Innovation
By translating precision pressure requirements across diverse skin types into a manufacturable applicator, we produced a home device robust enough for daily self-use.
Microneedle Patch Applicator
Client
Confidential
Practice Areas
Core Disciplines
Overview
The client selected Triple Ring to design a reusable applicator supporting the delivery of a novel micro-needle patch for transdermal drug administration. The system was intended for patient-administered use in home settings and required consistent mechanical performance to ensure reliable drug delivery.
The resulting combination product integrated a reusable applicator with a micro-needle patch system designed to enable uniform pressure application, supporting consistent adhesion and controlled dosing across diverse patient populations.
Challenge
The client developed a microneedle-based transdermal patch that required significantly greater uniformity of application pressure compared to traditional adhesive patches. Achieving reliable drug delivery required development of a reusable applicator capable of delivering consistent mechanical force during use.
The applicator needed to function effectively across a wide range of skin types, including variations in thickness, age, moisture content, and anatomical placement. In addition to performance requirements, the design needed to meet durability expectations for repeated home use while maintaining low production cost.
Microneedle Patch Applicator
Overview
The client selected Triple Ring to design a reusable applicator supporting the delivery of a novel micro-needle patch for transdermal drug administration. The system was intended for patient-administered use in home settings and required consistent mechanical performance to ensure reliable drug delivery.
The resulting combination product integrated a reusable applicator with a micro-needle patch system designed to enable uniform pressure application, supporting consistent adhesion and controlled dosing across diverse patient populations.
Challenge
The client developed a microneedle-based transdermal patch that required significantly greater uniformity of application pressure compared to traditional adhesive patches. Achieving reliable drug delivery required development of a reusable applicator capable of delivering consistent mechanical force during use.
The applicator needed to function effectively across a wide range of skin types, including variations in thickness, age, moisture content, and anatomical placement. In addition to performance requirements, the design needed to meet durability expectations for repeated home use while maintaining low production cost.
Client
Confidential
Practice Areas
Core Disciplines
Solution
Triple Ring applied interdisciplinary expertise across materials science, mechanical engineering, and life sciences to design an applicator capable of delivering controlled pressure during patch placement. The development effort focused on optimizing performance across diverse user conditions while maintaining manufacturability and reliability.
Key development efforts included:
- Designing precision mechanical systems capable of delivering uniform pressure during patch application
- Selecting materials optimized for durability, manufacturability, and patient-safe use
- Engineering applicator geometry to accommodate variation in skin thickness, moisture, and elasticity
- Validating device performance across simulated patient-use conditions
Outcome
Triple Ring delivered a reusable applicator integrated with a micro-needle array patch, forming a single-entity combination product designed for intracutaneous drug delivery. The system enabled rapid drug absorption while supporting consistent dosing performance.
The completed applicator enabled the client to advance into clinical trials and demonstrate the effectiveness of the technology to healthcare stakeholders. The underlying technology was ultimately acquired by a vaccine manufacturer, supporting continued development and commercialization.
Triple Ring Talent
The Story Behind the Innovation
At Triple Ring, we draw on a deep bench of expertise across diverse disciplines matched to each innovation challenge. For this project, our team combined mechanical engineering, materials science, and life sciences expertise to design a reusable applicator capable of delivering consistent, uniform pressure across diverse patient skin types — enabling reliable transdermal drug delivery in home settings.
Walt and Gabe collaborated with many talented colleagues across Triple Ring on this project.
Walt Cecka
Medical Device Design & Translational Medicine
Walt Cecka brings decades of experience translating novel medical technologies into first-to-market products. He works closely with innovators to shape early concepts into structured development programs that advance patient care across a wide range of clinical applications.
Gabriel Chow, PhD
Materials Characterization & Development
Dr. Gabe Chow specializes in materials characterization and mechanical system development across macro to nanoscale environments. His work supports the design, testing, and reliability of advanced materials and mechanical systems, helping translate innovative concepts into durable, real-world solutions.