A scientist in a lab coat and gloves examines a vial near a Beckman Coulter Life Sciences Cytoflex flow cytometry analyzer, with data from algorithm development displayed on a computer screen in a modern laboratory setting.
Beckman Coulter logo featuring a stylized circular design next to the company name in bold, uppercase letters.
Key Innovation Advanced algorithms multiplied analytical power fivefold — without new hardware.

Flow Cytometer Data Analysis

Client

Beckman Coulter Life Sciences

Overview

The CytoFLEX platform from Beckman Coulter Life Sciences is a market-leading flow cytometry platform designed to provide high sensitivity, strong resolution, and flexible configuration options across a wide range of applications. Built to support advanced sample analysis and regulatory workflows, the platform integrates CytExpert acquisition and analysis software and supports features such as multi-color detection and high-throughput processing.

To expand the platform’s analytical capabilities and strengthen its competitive position against third-party software solutions, Beckman Coulter Life Sciences partnered with Triple Ring to develop advanced data analysis algorithms supporting new high-value customer use cases.

Challenge

A key driver of the CytoFLEX platform’s longstanding market success is its sophisticated data analysis software suite, which allows users to predict unknown properties of their test samples. At project initiation, Triple Ring was tasked with designing algorithms to expand the number of high-value customer use cases from two to ten.

Beckman Coulter Life Sciences sought to capture market value held by third-party solutions while maintaining performance, flexibility, and speed of development across multiple technical disciplines.

Solution

Triple Ring applied cross-disciplinary expertise in optics, simulation, and system design to improve performance and manufacturability.

Key technical efforts included:

  • Optimizing optical subsystem design to improve signal sensitivity
  • Developing analytical models to predict system performance across configurations
  • Supporting integration of acquisition and analysis software workflows
  • Refining system architecture to improve manufacturability and yield
Three white and blue laboratory analyzers of varying sizes are arranged in a row on a plain background. The devices have a modern design with a hexagonal dot pattern on the front panels.

Outcome

The expanded analytics capabilities enabled Beckman Coulter Life Sciences to flexibly support multiple high-value customer use cases, strengthening the competitive position of the CytoFLEX platform and enabling future growth.

The collaboration produced valuable intellectual property and enhanced software capabilities that positioned the platform to capture market share previously held by third-party solutions.

Triple Ring Talent

The Story Behind the Collaboration

At Triple Ring, we draw on a deep bench of expertise across diverse disciplines matched to each innovation challenge. For this project, our team blended deep optics knowledge with advanced algorithm development, data science, and software engineering — expanding the CytoFLEX platform’s analytical capabilities from two to ten high-value customer use cases and capturing market share previously held by third-party solutions.

Daniel and Hailey collaborated with many talented colleagues across Triple Ring and Beckman Coulter on this project.

Meet our team
A portrait of Daniel Badali, a smiling man with glasses and a beard against a gray background.

Daniel Badali, PhD

Optics & Applied Physics

Dr. Daniel Badali brings deep expertise in advanced algorithms, optics, and radiation physics. His work bridges software and hardware, enabling complex simulation, imaging, and sterilization technologies that help turn sophisticated concepts into reliable medical solutions.

A portrait of Hailey Gryka, a woman with glasses and long curly hair smiling against a gray background.

Hailey Gryka

Bioinstrumentation & Data Science

Hailey Gryka brings expertise at the intersection of bioinstrumentation and data science. Her work spans device design, data processing, and system validation, helping teams move seamlessly from early concepts to manufacturable, reliable solutions.

A patient in Aim Medical Robotics' MRI-compatible surgical robot, nested inside a white MRI machine with physician in the background.
Logo with large white letters "AiM" on the left and smaller "MEDICAL ROBOTICS" on the right, featured in Triple Ring Technologies' case study on our technical product development of an MRI-compatible surgical robot, all on a light gray background.
Key Innovation First-principles robotics delivered precise motion control inside an MRI.

MRI-Compatible Robotics

Client

AiM Medical Robotics

Overview

AiM Medical Robotics engaged Triple Ring to develop a portable robotic system capable of performing neurosurgical procedures simultaneously with magnetic resonance imaging (MRI).

The resulting prototype established the technical foundation for an MRI-compatible robotic platform designed to support image-guided neurosurgery.

Challenge

MRI environments rely on strong magnetic fields that prohibit the use of ferromagnetic materials commonly found in traditional robotic systems. Additionally, the limited physical space inside MRI systems imposed strict form factor constraints.

These requirements demanded innovative design strategies to enable reliable robotic motion and positioning inside the MRI environment.

Solution

Triple Ring applied first-principles engineering and multidisciplinary design expertise to create an MRI-compatible robotic system.

Key elements of the solution included:

  • Design of multi-axis robotic systems optimized for MRI environments
  • Application of MRI physics principles to guide system architecture
  • Development of MRI-compatible components and assemblies
  • Rapid prototyping and testing to validate system performance
  • Engineering solutions addressing constrained spatial and material limitations
A photograph of a functional prototype of AiM Medical Robotics' MRI-compatible neurosurgical robot with a black mannequin head shown for scale.
A patient with eyes closed in AiM Medical Robotics' MRI-compatible neurosurgical robot and MRI machine.

Outcome

The collaboration produced a prototype robotic system with four degrees of freedom, establishing the basis for AiM Medical Robotics’ MRI-compatible neurosurgical platform.

The system demonstrated the feasibility of robotic-assisted neurosurgery within MRI environments and enabled further development of image-guided surgical technologies.

Triple Ring Talent

The Story Behind the Innovation

At Triple Ring, we draw on a deep bench of expertise across diverse disciplines matched to each innovation challenge. For this project, our team applied MRI physics, multidisciplinary robotic design, and rapid prototyping to develop a four-axis robotic system capable of performing neurosurgical procedures inside a live MRI environment.

Chris and Chris collaborated with many talented colleagues across Triple Ring and AiM Medical Products on this project.

Meet our team
A portrait of Christopher Mitchell, a smiling man with gray hair wearing a patterned shirt.

Chris Mitchell, PhD

Bio and Electrical Engineering & Program Management

Dr. Chris Mitchell brings deep experience leading multidisciplinary teams developing complex imaging and medical device systems. His work focuses on guiding technical programs from concept through implementation, helping translate advanced technologies into reliable, real-world solutions.

A portrait of Chris Todd, a smiling man wearing a blue polo shirt.

Chris Todd

Mechanical Engineering

Chris Todd focuses on biomedical diagnostics and precision instrumentation, integrating fluidics, optics, and mechanical systems. His work supports the development of regulated medical technologies from early concepts through manufacturing, helping teams deliver reliable diagnostic solutions at scale.

A person holding a Hound Labs device displaying a "pass" result for a cannabis breathalyzer test.
Hound Labs logo featuring a stylized dog head in a circle next to the company name in bold capital letters, as highlighted in Triple Ring Technologies' case study on our technical product development of Hound Labs' cannabis breathalyzer system.
Key Innovation Microfluidic lab-on-a-chip technology brought clinical-grade THC detection out of the lab.

Cannabis Breathalyzer System

Client

Hound Labs

Overview

Hound Labs engaged Triple Ring to invent a portable breath analyzer capable of detecting recent marijuana use. The system was developed to support point-of-use testing in law enforcement and workplace environments requiring reliable impairment detection.

Starting from an early concept sketch, Triple Ring collaborated with Hound Labs to develop a high-sensitivity breathalyzer platform combining chemical detection and portable instrumentation technologies.

Challenge

The system needed to detect Δ-9 THC in exhaled breath with clinical-grade sensitivity while maintaining portability and reliability in field conditions.

In addition to engineering challenges, the project required validation of THC pharmacodynamics in breath, including generation of peer-reviewed scientific evidence supporting detection feasibility.

Four conceptual sketches of the handheld Hound Labs cannabis breathalyzer device with different design features highlighted.
Exploded view diagram showing the components of the Hound Labs handheld cannabis breathalyzer, highlighting its interior parts and mechanical design.

Solution

Triple Ring assembled multidisciplinary development teams to design and validate a fully integrated breath analysis platform combining microfluidic sampling and portable device technologies.

Development efforts included:

  • Designing a portable breath capture device optimized for reliable sample collection
  • Engineering microfluidic lab-on-a-chip cartridges supporting sensitive compound detection
  • Integrating control station hardware capable of processing and analyzing captured samples
  • Supporting validation activities that produced peer-reviewed pharmacodynamic data
  • Developing prototype systems suitable for demonstration, testing, and continued product development
A portable cannabis breathalyzer kit by Hound Labs with carrying case and digital handheld device.

Outcome

Triple Ring delivered fully functioning prototype systems consisting of a breath capture device, control station, and microfluidic cartridges.

The system produced clinical-grade data at the point of use, supporting detection of recent marijuana use and enabling development of a first-in-class breath-based detection platform.

Triple Ring Talent

The Story Behind the Innovation

At Triple Ring, we draw on a deep bench of expertise across diverse disciplines matched to each innovation challenge. For this project, our team combined microfluidic engineering, biological sensing, portable instrumentation, and clinical validation expertise to develop a first-in-class breath-based THC detection platform capable of delivering clinical-grade results at the point of use.

David and Kevin collaborated with many talented colleagues across Triple Ring and Hound Labs on this project.

Meet our team
A portrait of David Shack, a smiling man wearing glasses and a blue checked shirt against a blurred background.

David Shack, PhD

Mechanical Engineering & Applied Sciences

Dr. David Shack directs the development of complex scientific measurement and analysis systems across multidisciplinary teams. His work integrates algorithms, software, fluidics, and optical technologies, helping advance tools that support precision research and clinical applications.

A portrait of Kevin Limtao, a smiling man with glasses wearing a blue-striped shirt.

Kevin Limtao

Biomedical & Systems Engineering

Kevin Limtao connects system requirements, architecture, and integration across complex medical and diagnostic technologies. His work helps teams align design, risk, and performance throughout the development lifecycle, ensuring systems function reliably from early concepts through deployment.

A conceptual rendering of the at-home diagnostic device next to a bathroom sink.
Key Innovation Quantitative optics in a lateral flow assay brought multiplexed diagnostics into the home.

At-Home Quantitative Diagnostics

Client

BARDA

Overview

The Biomedical Advanced Research and Development Authority (BARDA) selected Triple Ring to design, build, and test a low-cost quantitative biomarker detection platform intended for at-home and low-resource healthcare settings. The system was developed to support multiplexed biomarker analysis using compact, user-friendly instrumentation.

The resulting platform integrates biological sensing, embedded electronics, and optical detection technologies into a portable diagnostic system designed to support lab-at-home, point-of-care, and direct-to-consumer workflows.

Challenge

BARDA identified the need for a low-cost diagnostic platform capable of delivering quantitative biomarker measurements outside traditional laboratory environments. The system needed to support multiplexed testing while remaining accessible for use in resource-limited settings and CLIA-waived environments.

Achieving this capability required integration of complex biological, optical, and electronic subsystems into a compact and manufacturable design. The platform also needed to extend the measurable range of lateral flow immunoassays while maintaining usability and cost targets suitable for broad deployment.

An isolated conceptual 3D rendering of the at-home diagnostic device next to a cup with blue liquid
Illustration showing two steps: 1) A test strip is dipped into a liquid in a cup. 2) The strip is inserted into a small, rectangular digital device.

Solution

Triple Ring applied multidisciplinary expertise across biological sciences, engineering, and embedded systems to develop a scalable diagnostic platform capable of delivering quantitative results from multiplexed lateral flow assays.

Development efforts focused on:

  • Designing multiplexed lateral flow assay (LFA) detection systems capable of quantifying biomarker concentrations
  • Integrating biological, electrical, mechanical, optical, and embedded software subsystems into a unified platform
  • Developing workflows suitable for CLIA-waived, point-of-care, and at-home diagnostic environments
  • Extending the quantitative measurement range beyond that of conventional lateral flow assay readers
  • Conducting system-level integration and verification to support development of a handheld diagnostic platform

Outcome

Triple Ring delivered a functional multiplexed diagnostic platform capable of quantifying biomarker concentrations across multiple test channels. The system demonstrated improved quantitative measurement range compared to conventional lateral flow assay readers.

The platform supported deployment across diverse clinical environments, including at-home and point-of-care settings. Ongoing development efforts include system integration and testing of a handheld version designed to further expand accessibility and usability in remote and low-resource healthcare environments.

Triple Ring Talent

The Story Behind the Innovation

At Triple Ring, we draw on a deep bench of expertise across diverse disciplines matched to each innovation challenge. For this project, our team combined biological sciences, optical detection, embedded electronics, and diagnostic platform engineering to develop a low-cost multiplexed biomarker detection system capable of delivering quantitative lab-grade results in at-home and resource-limited healthcare settings.

Rachel and Chris collaborated with many talented colleagues across Triple Ring and BARDA on this project.

Meet our team
Smiling woman with long blonde hair wearing a blue shirt and dark blazer, photographed against a blurred gray background.

Rachel Gerver, PhD

Bioengineering & Applied Science and Systems

Dr. Rachel Gerver advances microfluidic and point-of-care technologies from early development into real-world application. Her work spans technical leadership and systems development, helping teams bring complex innovations to market where they can deliver meaningful impact.

A portrait of Chris Todd, a smiling man wearing a blue polo shirt.

Chris Todd

Mechanical Engineering

Chris Todd focuses on biomedical diagnostics and precision instrumentation, integrating fluidics, optics, and mechanical systems. His work supports the development of regulated medical technologies from early concepts through manufacturing, helping teams deliver reliable diagnostic solutions at scale.

A person holding a transdermal patch applicator
Key Innovation Precision pressure engineering across skin types put daily self-dosing in patients' hands.

Microneedle Patch Applicator

Client

Confidential

Overview

The client selected Triple Ring to design a reusable applicator supporting the delivery of a novel micro-needle patch for transdermal drug administration. The system was intended for patient-administered use in home settings and required consistent mechanical performance to ensure reliable drug delivery.

The resulting combination product integrated a reusable applicator with a micro-needle patch system designed to enable uniform pressure application, supporting consistent adhesion and controlled dosing across diverse patient populations.

Challenge

The client developed a microneedle-based transdermal patch that required significantly greater uniformity of application pressure compared to traditional adhesive patches. Achieving reliable drug delivery required development of a reusable applicator capable of delivering consistent mechanical force during use.

The applicator needed to function effectively across a wide range of skin types, including variations in thickness, age, moisture content, and anatomical placement. In addition to performance requirements, the design needed to meet durability expectations for repeated home use while maintaining low production cost.

3D view of an innovative commination medical device microneedle patch applicator for transdermal drug delivery. White and orange ergonomic handheld device with attachment
Diagram of a transdermal patch delivering medication through the skin with drug-coated tips penetrating the epidermis.

Solution

Triple Ring applied interdisciplinary expertise across materials science, mechanical engineering, and life sciences to design an applicator capable of delivering controlled pressure during patch placement. The development effort focused on optimizing performance across diverse user conditions while maintaining manufacturability and reliability.

Key development efforts included:

  • Designing precision mechanical systems capable of delivering uniform pressure during patch application
  • Selecting materials optimized for durability, manufacturability, and patient-safe use
  • Engineering applicator geometry to accommodate variation in skin thickness, moisture, and elasticity
  • Validating device performance across simulated patient-use conditions
A four-panel illustration showing the steps for using a handheld transdermal patch applicator: from resting position, opening, applying on skin, to pressing the dispenser button.

Outcome

Triple Ring delivered a reusable applicator integrated with a micro-needle array patch, forming a single-entity combination product designed for intracutaneous drug delivery. The system enabled rapid drug absorption while supporting consistent dosing performance.

The completed applicator enabled the client to advance into clinical trials and demonstrate the effectiveness of the technology to healthcare stakeholders. The underlying technology was ultimately acquired by a vaccine manufacturer, supporting continued development and commercialization.

Triple Ring Talent

The Story Behind the Innovation

At Triple Ring, we draw on a deep bench of expertise across diverse disciplines matched to each innovation challenge. For this project, our team combined mechanical engineering, materials science, and life sciences expertise to design a reusable applicator capable of delivering consistent, uniform pressure across diverse patient skin types — enabling reliable transdermal drug delivery in home settings.

Walt and Gabe collaborated with many talented colleagues across Triple Ring on this project.

Meet our team
A portrait of of Walt Cecka, a smiling man with short hair wearing a plaid shirt against a blurred background.

Walt Cecka

Medical Device Design & Translational Medicine

Walt Cecka brings decades of experience translating novel medical technologies into first-to-market products. He works closely with innovators to shape early concepts into structured development programs that advance patient care across a wide range of clinical applications.

A portrait of Gabe Chow, a smiling man wearing glasses and a blue jacket with a blurred background.

Gabriel Chow, PhD

Materials Characterization & Development

Dr. Gabe Chow specializes in materials characterization and mechanical system development across macro to nanoscale environments. His work supports the design, testing, and reliability of advanced materials and mechanical systems, helping translate innovative concepts into durable, real-world solutions.

A lab technician in a white coat holds blood samples near laboratory equipment, showcasing the legacy IVD product modernization process while ensuring 510(k) compliance.
Key Innovation Reverse engineering lost design history made a Special 510(k) viable.

IVD Platform Refresh

Client

Fortune 500 IVD Company

Overview

A Fortune 500 diagnostics manufacturer worked with Triple Ring to modernize a legacy in vitro diagnostic (IVD) platform facing component obsolescence and software limitations. The project focused on refreshing the system architecture while maintaining regulatory equivalency with an existing FDA-cleared product.

The resulting platform replaced obsolete hardware, migrated legacy software, and introduced updated industrial design elements while preserving compatibility with established manufacturing and regulatory pathways.

Challenge

The client faced the obsolescence of critical hardware components, including single-board computers and microcontrollers, within an existing diagnostic platform. Compounding the challenge, original firmware source code was unavailable, and institutional knowledge associated with the system had diminished over time.

In addition to restoring functionality, the refreshed system needed to maintain regulatory equivalence to the original device in order to qualify for a Special 510(k) submission. This requirement demanded careful reverse engineering, system validation, and modernization without introducing unintended performance deviations.

Close-up of a computer hard drive circuit board, showcasing blue circuitry and an attached circular component with orange connectors, reminiscent of the precision needed in legacy IVD product modernization and 510(k) compliance.
A person is sitting at a desk using a laptop and monitor, both displaying lines of code. A tablet with a blank page is also on the desk, suggesting plans for legacy IVD product modernization.

Solution

Triple Ring implemented a structured modernization strategy combining reverse engineering, hardware redesign, and software migration. The development effort focused on preserving functional equivalency while introducing modern components and improving long-term maintainability.

Development efforts included:

  • Reverse-engineering legacy hardware and firmware to recover system functionality and requirements
  • Migrating existing software to a modern operating system architecture
  • Replacing obsolete components while maintaining compatibility with legacy subsystems
  • Updating mechanical and electrical subassemblies to support manufacturing continuity
  • Preparing validation and documentation packages supporting regulatory equivalence requirements

Outcome

Triple Ring delivered a fully refreshed IVD platform supported by a comprehensive regulatory submission package demonstrating equivalency to the original FDA-cleared device. The updated system maintained functional continuity while addressing long-term hardware and software sustainability.

The refreshed design integrated seamlessly into existing manufacturing workflows, enabling uninterrupted production and maintaining cost targets. The modernization effort positioned the platform for continued market competitiveness while ensuring regulatory compliance and operational reliability.

Triple Ring Talent

The Story Behind the Innovation

At Triple Ring, we draw on a deep bench of expertise across diverse disciplines matched to each innovation challenge. For this project, our team combined reverse engineering, embedded systems, software migration, regulatory strategy, and industrial design expertise to modernize a legacy IVD platform — restoring long-term sustainability while maintaining full regulatory equivalency with the original FDA-cleared device.

Rob and Anne collaborated with many talented colleagues across Triple Ring on this project.

Meet our team
A portrait of Robert de Saint Phalle, a smiling man wearing a blue shirt, with a blurred background.

Robert de Saint Phalle

Interdisciplinary Product Design

Robert de Saint Phalle shapes product design strategies that connect engineering, user experience, and emerging technologies. His work helps teams translate complex ideas into thoughtful, functional products that bring new technologies to life.

A photo of Anne Preut, a woman with wavy brown hair smiling, wearing a green top and small gold hoop earrings, against a blurred gray background.

Anne Preut

Biomedical & Systems Engineering

Anne Preut leads systems engineering efforts that integrate hardware, firmware, assays, and fluidics across complex diagnostic technologies. Her work aligns cross-functional teams throughout the development lifecycle, helping ensure systems perform reliably from early feasibility through production.

Two medical professionals examine brain scans on monitors. A patient lies on a CT scanner in the background.
Key Innovation Lifecycle strategy extended viability without sacrificing manufacturing continuity or IP.

Maximize Legacy Product Value

Client

Large Corporations

Background

Sustaining engineering is more than product maintenance and implementing market requests; it’s a strategic approach to keeping legacy products competitive and profitable over decades. At Triple Ring, we don’t simply maintain legacy products – we transform them to meet modern demands.  We add high-value features like AI in addition to updating industrial design, increasing reliability, and lowering production costs.  We also address evolving regulatory risk, including cyber security, while carefully protecting core intellectual property.

Modernization of Legacy Products

Keeping products ahead in the market through:

  • AI design and integration
  • Cybersecurity software migrations
  • Performance upgrades and added functionality
  • Refreshed industrial design, usability, and aesthetics
  • Supply chain security
Soldering prototype PCBA board.
A scientist uses a pipette in a lab, with DNA sequences displayed on a screen in the background.

AI Enhancement

Enhancing legacy systems with physics-based AI improves performance, accuracy, and efficiency, and supports predictive maintenance. These features dramatically extend product lifespan without costly hardware upgrades. Triple Ring has the experience and expertise in AI algorithm design and integration to modernize products and create new valuable solutions for customers.

Supply Chain Optimization

Updating and optimizing supply chains addresses obsolescence, reduces cost, increases production yields and product reliability. Triple Ring and our partners ensure smooth production, minimize disruptions, and unlock new cost-saving opportunities for your legacy products.

Why Partner with Triple Ring?

Successful products often outlive the teams that launched them resulting in critical knowledge gaps within organizations that grow over time.  Product companies need a trusted partner with deep expertise in reverse engineering, modern regulatory standards, supply chain access, and expertise in AI.  Partnering with Triple ring unlocks these benefits, and importantly, saves product companies the cost and schedule delays associated with rebuilding engineering teams.  Ensure product success and optimal return on investment over the long haul by engaging with Triple Ring on your next sustaining engineering project.